Thursday, 17 August 2017

Coptis chinensis (Berberine) dược liệu kháng L1210

Coptis chinensis (Berberine) dược liệu kháng L1210

From Wikipedia, the free encyclopedia
Chinese goldthread
Scientific classificatione
Kingdom:Plantae
Clade:Angiosperms
Clade:Eudicots
Order:Ranunculales
Family:Ranunculaceae
Genus:Coptis
Species:C. chinensis
Binomial name
Coptis chinensis
Franch.[1]
Coptis chinensis, the Chinese goldthread, is a species of goldthread native to China.

Etymology[edit]

Chemical constituents[edit]

The rhizomes of Coptis chinensis are used in Traditional Chinese Medicine and serve as a source for the isoquinoline alkaloids berberine,[3] palmatine, and coptisine among others.

Traditional uses[edit]

Coptis chinensis is one of the 50 fundamental herbs used in traditional Chinese medicine, where it is called duǎn è huánglián (Chinese: 短萼黄连).

Pharmacology[edit]

A variety of pharmacological effects of Coptis chinensis extracts or its chemical components have been reported, but the relevance of these in vitro and animals studies to human health are unknown. For example, a 1996 in vitro study found Coptis chinensis extracts to be effective against the gastrointestinal parasite Blastocystis hominis.[4] A study in rats suggested Coptis and berberine (the primary alkaloid in Coptis) are potential agents for preventing intestinal injury.[5] Berberine may also have anti-atherosclerosis effects.[6] Berberine and basic extracts of Coptis chinensis also have demonstrated positive effects in an animal model of neurodegeneration.[7] Animal studies suggest Coptis chinensis rhizomes may help with the pain of irritable bowel syndrome.[8]

Other uses[edit]

Because of the strong coloring quality of berberine, it has been traditionally used as a dye, especially for wool and other fibers.[9]

See also[edit]

Kết quả hình ảnh cho Coptis chinensis
Kết quả hình ảnh cho Coptis chinensis
Kết quả hình ảnh cho Coptis chinensisKết quả hình ảnh cho Coptis chinensis
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Phellodendron amurense (Berberine) dược liệu kháng L1210

Phellodendron amurense (Berberine) dược liệu kháng L1210

From Wikipedia, the free encyclopedia
Phellodendron
Phellodendron amurense Morton.jpg
Phellodendron amurense
Morton Arboretum acc. 568-27*3
Scientific classification
Kingdom:Plantae
(unranked):Angiosperms
(unranked):Eudicots
(unranked):Rosids
Order:Sapindales
Family:Rutaceae
Genus:Phellodendron
Species:P. amurense
Binomial name
Phellodendron amurense
Rupr.[1]
Phellodendron amurense is a species of tree in the family Rutaceae, commonly called the Amur cork tree. It is a major source of huáng bò (Chinese: 黄柏 or 黄檗), one of the 50 fundamental herbs used in traditional Chinese medicine. The Ainu people used this plant, called shikerebe-ni, as a painkiller.[2]
Native to eastern Asia; northern China, northeast China, Korea, Ussuri, Amur, and Japan, the Amur cork tree is considered invasive in many parts of North America. The State of Massachusetts lists it as a noxious weed.[3]
Autumn Foliage and Fruit

Medicinal use[edit]

Plant as used in Chinese herbology. Note the pictured is a photo of Licorice Root/ GanCao, not Phellodendron. (crude medicine)
It has been used as a Chinese traditional medicine for the treatment of meningitis, bacillary dysentery, pneumonia, tuberculosis, and liver cirrhosis.[4][5]
Used orally to treat abdominal pain, diarrhoea, gastroenteritis and urinary tract infections. Berberine has been shown to be effective for the treatment of bacterially-induced diarrhoea and ocular trachoma. and cutaneous leishmaniasis[6]Phellodendron amurense may protect cartilage against osteoarthritis progression.[7] It may prove to be a potentially important chemopreventive agent for lung cancer.[8]
Phellodendron amurense is able to inhibit prostatic contractility suggesting that it may be useful in the treatment of urological disorders caused by prostatic urethral obstruction such as benign prostatic hyperplasia (BPH).[9] Nexrutine (bark extract from Phellodendron amurense) may have potential to prevent prostate tumor development.[10]
Proprietary extracts of Magnolia officinalis and Phellodendron amurense may help overweight/obese people.[11]
Compounds in the leaves (quercetin, quercetin-3-O-beta-D-glucoside, quercetin-3-O-beta-D-galactoside and kaempferol-3-O-beta-D-glucoside) demonstrated significant free radical scavenging activity comparable to vitamin E.[12]

Oil[edit]

Amur cork tree fruit oil is a pressed oil extracted from the fruit of Phellodendron amurense. The bark of the tree is an important herbal medicine in China. The oil has insecticidal properties similar to pyrethrum.[13] The oil contains a variety of biologically active substances, including flavonoids (diosmin), alkaloids (berberine, yatroriccin, palmatine), saponins and coumarins. Medicinal applications of the oil include treatment of pancreatitis, reduction of cholesterol and sugar in blood and the treatment of various skin diseases.[14]

Chemistry[edit]

Essential oils:[15]
Amurensin, a tert-amyl alcohol derivative of kaempferol 7-O-glucoside, can be found in P. amurense.[16]

Gallery[edit]

  • Leaf
    •  
  • Tree
    •  
  • Bark

See also[edit]

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Xanthorhiza (Berberine) dược liệu kháng L1210

Xanthorhiza (Berberine) dược liệu kháng L1210

From Wikipedia, the free encyclopedia
  (Redirected from Xanthorhiza simplicissima)
Yellowroot
Yellowroot- Xanthorhiza simplicissima.JPG
Yellowroot flowers in spring
Scientific classificatione
Kingdom:Plantae
Clade:Angiosperms
Clade:Eudicots
Order:Ranunculales
Family:Ranunculaceae
Subfamily:Coptidoideae
Genus:Xanthorhiza
Marshall
Species:X. simplicissima
Binomial name
Xanthorhiza simplicissima
Marshall
Synonyms
Xanthorhiza apiifolia L'Hér.
Xanthorhiza simplicissima (yellowroot) is the only member of the genus Xanthorhiza, and one of very few genera in the family Ranunculaceae with a woody stem (the other notable example being Clematis). It is native to the eastern United States from Maine south to northern Florida and west to Ohio and eastern Texas. It contains the alkaloid berberine, which has a number of traditional and contemporary uses for dyeing and medicine.
The genus name as well as the common name refer to the plant's yellow roots (xantho- meaning "yellow" and rhiza meaning "root"), which was used to produce a yellow dye by Native Americans. The species name refers to the simple (not branched) root.
In the wild, it grows on the edges of streams in sandy soil under a canopy of dappled sunlight. In cultivation, it is often provided with more sunlight so that the fall colors are more vivid. It is a subshrub, reaching 20–70 centimetres (8–28 in) (rarely 90 centimetres (35 in)) in height, with stems up to 6 millimetres (0.24 in) diameter. The leaves are spirally arranged, 10–18 centimetres (4–7 in) long, each divided into 5 toothed leaflets, and flowers emerge only from the upper portion of the unbranched stem. The flowers are produced in broad panicles 6–20 centimetres (2–8 in) long, each flower small, star-shaped, reddish brown to purple brown, with five petals.
Yellowroot propagates asexually by sending out many underground runners, and it reproduces sexually with seeds.
Yellowroot is comparatively rare in British gardens, although E.H. Wilson and E.A. Bowles are among distinguished plantsmen to have championed its merits. It was grown by Bowles in his garden at Myddelton House, near Enfield, Middlesex, and gardens that currently cultivate it include the Savill Garden at Windsor, Berkshire and the Westonbirt Arboretum near Tetbury, Gloucestershire.[1] Wilson, who regarded yellowroot as one of the best plants for hardy deciduous ground cover, also described (in 1923) its use in the Arnold Arboretum at Harvard University in Massachusetts.[2]
Yellowroot is considered an endangered species in Florida.
  • XanthorhizaSimplicissima.jpg
    •  
  • Closeup of yellowroot's flowers

References and external links[edit]

  1. Jump up^ Roy Lancaster in The Garden, volume 120, part 12, page 743 (December 1995).
  2. Jump up^ Wilson (1923) More Aristocrats of the Garden
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