Monday, 24 July 2017

Monarda fistulosa (Thymoquinone) dược liệu kháng MCF7

Monarda fistulosa (Thymoquinone) dược liệu kháng MCF7

From Wikipedia, the free encyclopedia
Wild bergamot
Purple Flower Wild Bergamot DSC 0172.JPG
Monarda fistulosa inflorescence
Scientific classification
Kingdom:Plantae
(unranked):Angiosperms
(unranked):Eudicots
(unranked):Asterids
Order:Lamiales
Family:Lamiaceae
Genus:Monarda
Species:M. fistulosa
Binomial name
Monarda fistulosa
L.
Monarda fistulosa, the wild bergamot or bee balm,[1] is a wildflower in the mint family (Lamiaceae) widespread and abundant as a native plant in much of North America.[2] This plant, with showy summer-blooming pink to lavender flowers, is often used as a honey plantmedicinal plant, and garden ornamental.[3] The species is quite variable, and several subspecies or varieties have been recognized within it.

Description and distribution[edit]

Monarda fistulosa (wild bergamot) plants, Ottawa, Ontario, Canada
Monarda fistulosa is an herbaceous perennial that grows from slender creeping rhizomes, thus commonly occurring in large clumps. The plants are typically up to 3 ft (0.9 m) tall, with a few erect branches. Its leaves are about 2-3 in (5–8 cm) long, lance-shaped, and toothed. Its compact flower clusters are solitary at the ends of branches. Each cluster is about 1.5 in (4 cm) long, containing about 20–50 flowers. Wild bergamot often grows in rich soils in dry fields, thickets, and clearings, usually on limy soil. The plants generally flower from June to September.[4]
Monarda fistulosa ranges from Quebec to the Northwest Territories and British Columbia, south to GeorgiaTexasArizonaIdaho, and northeastern Washington.
The plant is noted for its fragrance, and is a source of oil of thyme.[citation needed]

Taxonomy[edit]

Several varieties have been variously recognized within Monarda fistulosa, of which some have also been treated as subspecies or as distinct species. Some of the varieties are geographically widespread, and others are quite restricted in their ranges. Varieties include:
  • Monarda fistulosa var. brevis[5] – Smoke Hole bergamot (Virginia and West Virginia)[6][7]
  • Monarda fistulosa var. fistulosa – wild bergamot (widespread, primarily eastern and central North America)[8]
  • Monarda fistulosa var. longipetiolata – (Ontario and Quebec)[9]
  • Monarda fistulosa var. maheuxii – (Ontario)[10]
  • Monarda fistulosa var. menthifolia – (widespread, western North America, excluding Oregon and California)[11]
  • Monarda fistulosa var. mollis – (widespread, primarily eastern and central North America)[12]
  • Monarda fistulosa var. rubra – (eastern North America, uncommon)[13]
  • Monarda fistulosa, unnamed variety[14] – (Arkansas and Oklahoma)[15]
One authority states that Native Americans recognized four kinds of wild bergamot that had different odors.(Wood,1997)

Uses[edit]

Wild bergamot was considered a medicinal plant by many Native Americans including the Menominee, the Ojibwe, and the Winnebago (Ho-Chunk). It was used most commonly to treat colds, and was frequently made into a tea. Today, many families still use wild bergamot during the cold and flu season. The tea may be sweetened with honey, as it tends to be quite strong.[16]
The species of Monarda that may go under the common name "bee balm," including M. fistulosa, have a long history of use as a medicinal plant by Native Americans, including the Blackfoot. The Blackfoot recognized the plant's strong antiseptic action, and used poultices of the plant for skin infections and minor wounds.[citation needed]A tea made from the plant was also used to treat mouth and throat infections caused by dental caries and gingivitis.[citation needed] Bee balm is the natural source of the antiseptic thymol, the primary active ingredient in modern commercial mouthwash formulas. The Winnebago used a tea made from bee balm as a general stimulant.[citation needed] Bee balm was also used as a carminative herb by Native Americans to treat excessive flatulence.[17] Leaves were eaten boiled with meat and a concoction of the plant was made into hair pomade. The herb is considered an active diaphoretic (sweat inducer).
The essential oil of Monarda fistulosa was analyzed using mass spectrometry and arithmetical retention indices, and was found to contain p-cymene (32.5%), carvacrol(24.0%), thymol (12.6%), an aliphatic aldehyde (6.3%), the methyl ether of carvacrol (5.5%), α-pinene (3.5%), β-pinene (2.9%), sabinene hydrate (1.9%), α-terpinene(1.7%), citronellyl acetate (1.6%), and β-caryophyllene (1.1%).[18]

Nigella sativa (Thymoquinone) dược liệu kháng MCF7

Nigella sativa (Thymoquinone) dược liệu kháng MCF7

From Wikipedia, the free encyclopedia
Nigella sativa
Nsativa001Wien.jpg
Scientific classification
Kingdom:Plantae
(unranked):Angiosperms
(unranked):Eudicots
Order:Ranunculales
Family:Ranunculaceae
Genus:Nigella
Species:N. sativa
Binomial name
Nigella sativa
Synonyms[1]
  • Nigella cretica Mill.
The black caraway fruit is a large and inflated capsule composed of three to seven united follicles, each containing numerous seeds which are used as spice, sometimes as a replacement for black cumin (Bunium bulbocastanum).
black cumin seed

Etymology[edit]

The genus name Nigella is a diminutive of the Latin niger (black), referring to the seeds.[5]

Common names[edit]

Blackseed and black caraway may also refer to Bunium persicum.[7]

Culinary uses[edit]

The seeds of Nigella sativa are used as a spice in Indian and Middle Eastern cuisines. The black seeds taste like a combination of onions, black pepper and oregano. They have a pungent bitter taste and smell.[6]
The dry-roasted nigella seeds flavor curries, vegetables and pulses. It can be used as a "pepper" in recipes with pod fruit, vegetables, salads and poultry. In some cultures, the black seeds are used to flavor bread products. It is also used as part of the spice mixture panch phoron (meaning a mixture of five spices) and by itself in many recipes in Bengali cuisine and most recognizably in naan bread.[8] Nigella is also used in Armenian string cheese, a braided string cheese called majdouleh or majdouli in the Middle East.

History[edit]

Archaeological evidence about the earliest cultivation of N. sativa "is still scanty", but N. sativa seeds were found in several sites from ancient Egypt, including Tutankhamun's tomb.[9] Seeds were found in a Hittite flask in Turkey from the second millennium BCE.[10]
N. sativa may have been used as a condiment of the Old World to flavor food.[9] The Persian physician, Avicenna, in his Canon of Medicine, described N. sativa as a treatment for dyspnea.[11]

Chemistry[edit]

Research[edit]

Preliminary studies have investigated claims from traditional medicine that N. sativa has efficacy as a therapy, mainly using the seed oil extract, volatile oil, and isolated constituent thymoquinone.[13] One meta-analysis of clinical trials found weak evidence that N. sativa has a short-term benefit on lowering systolic and diastolic blood pressure, and another found limited evidence that various extracts of black seed can reduce triglycerides, LDL and total cholesterol while raising HDL cholesterol.[14][15]