KATO III cells
Catalog #:
C0023001Shipping advice:
Use only Express Delivery (overnight) for cell lines. International shipping rate please contact us for detailsDisease:
Gastric carcinomaOrigin:
Derived from metastatic pleural effusion; supraclavicular and axillary lymph nodes and Douglas cul-de-sacSpecies:
Homo sapiensTissue:
StomachMorphology:
SpericalProperties:
Mixed Suspension and Adherent for long term cultureCytogenic data:
Tumorigenic; The stemline chromosome number is hypotetraploidPatient:
Male, Asian, 55 yrs of ageMedium:
IMDM + 20% FBSSubculture:
1:2 to 1:8 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°CFreezing Medium:
Complete culture medium supplemented with 5% (v/v) DMSOBiosafety Level:
ISterility:
Bacteria: NegativeYeast: Negative
Mycoplasma: Negative
Pathogens:
HIV: NegativeHepatitis B: Negative
Hepatitis C: Negative
Protein Expression:
Isoenzymes:
AK-1, 1; ES-D, 1; G6PD, B; GLO-I, 2; PGM1, 1; PGM3, 1;DNA Profile (STR):
Amelogenin: X; CSF1PO: 7,11; D13S317: 8,12; D16S539: 10,12; D5S818: 10,11; D7S820: 8,12; THO1: 7,9; TPOX: 11; vWA: 14,16Mutations in KATO III CellsReferences for KATO III cells:
1. Hofbauer, R., Pasching, E., Moser, D., and Frass, M. Heparin-binding epidermal growth factor expression in KATO-III cells after Helicobacter pylori stimulation under the influence of strychnos Nux vomica and Calendula officinalis. Homeopathy, 99: 177-182.2. Itoh, H., Ito, H., and Hibasami, H. Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells. Oncol Rep, 20: 1359-1361, 2008.
3. Pazos, Y., Alvarez, C. J., Camina, J. P., and Casanueva, F. F. Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-III by obestatin. Growth Factors, 25: 373-381, 2007.
4. Hibasami, H., Takagi, K., Ishii, T., Tsujikawa, M., Imai, N., and Honda, I. Induction of apoptosis by rhapontin having stilbene moiety, a component of rhubarb (Rheum officinale Baillon) in human stomach cancer KATO III cells. Oncol Rep, 18: 347-351, 2007.
5. Matthews, G. M., Howarth, G. S., and Butler, R. N. Short-chain fatty acid modulation of apoptosis in the Kato III human gastric carcinoma cell line. Cancer Biol Ther, 6: 1051-1057, 2007.
6. Kasuga, T., Tabuchi, T., Shirato, K., Imaizumi, K., and Tomoda, A. Caspase-independent cell death revealed in human gastric cancer cell lines, MKN45 and KATO III treated with phenoxazine derivatives. Oncol Rep, 17: 409-415, 2007.
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