Biochanin A và prunetin cải thiện chức năng
http://www.genes-environment-inflammation.de/publication/biochanin-and-prunetin-improve-epithelial-barrier-function-intestinal-caco-2-cells
BIOCHANIN A VÀ PRUNETIN kháng Caco-2
Biochanin A
From Wikipedia, the free encyclopedia
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 | |
| Names | |
|---|---|
| IUPAC name
5,7-Dihydroxy-3-(4-methoxyphenyl)chromen-4-one
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| Other names
Biochanin
4'-Methylgenistein olmelin Biochanine A Biochanin-A Genistein 4-methyl ether 5,7-Dihydroxy-4'-methoxyisoflavone | |
| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.007.041 |
| KEGG | |
PubChem CID
| |
| Properties | |
| C16H12O5 | |
| Molar mass | 284.27 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is   ?) | |
| Infobox references | |
Biochanin A is an O-methylated isoflavone. It is a natural organic compound in the class of phytochemicals known as flavonoids. Biochanin A can be found in red clover [1] in soy, in alfalfa sprouts, in peanuts, in chickpea (Cicer arietinum) and in other legumes.
Biochanin A is classified as a phytoestrogen and has putative benefits in dietary cancer prophylaxis.[medical citation needed] It has also been found to be a weak inhibitor of fatty acid amide hydrolase in vitro.[2]
Metabolism[edit]
The enzyme biochanin-A reductase uses dihydrobiochanin A and NADP+ to produce biochanin A, NADPH, and H+. The enzyme isoflavone-7-O-beta-glucoside 6"-O-malonyltransferase uses malonyl-CoA and biochanin A 7-O-β-D-glucoside to produce CoA and biochanin A 7-O-(6-O-malonyl-β-D-glucoside).
Prunetin
From Wikipedia, the free encyclopedia
 | |
 | |
| Names | |
|---|---|
| IUPAC name
5-hydroxy-3-(4-hydroxyphenyl)-7-methoxychromen-4-one
| |
| Other names
Prunusetin
4',5-dihydroxy-7-methoxyisoflavone 5,4'-dihydroxy-7-methoxyisoflavone | |
| Identifiers | |
| |
3D model (JSmol)
| |
| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.008.199 |
| EC Number | 209-018-5 |
| KEGG | |
PubChem CID
| |
| Properties | |
| C16H12O5 | |
| Molar mass | 284.26 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
 verify (what is ?) | |
| Infobox references | |
Prunetin is an O-methylated isoflavone, a type of flavonoid. It has been isolated for the first time by Finnemore in 1910 in the bark of Prunus emarginata (the Oregon cherry).[1] Prunetin isolated from pea roots can act as an attractant for Aphanomyces euteiches zoospores.[2] It is also an allosteric inhibitor of human liver aldehyde dehydrogenase.[3]
Glycosides[edit]
- 8-C-glucosyl prunetin, isolated from the leaves of Dalbergia hainanensis[4]
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