Thursday, 3 August 2017

Turmeric-Curcuma longa (Curcumin) dược liệu kháng HL60

Turmeric-Curcuma longa (Curcumin) dược liệu kháng HL60

From Wikipedia, the free encyclopedia
Turmeric
Turmeric inflorescence.jpg
Inflorescence of Curcuma longa
Turmeric BNC.jpg
Processed turmeric
Scientific classificatione
Kingdom:Plantae
Clade:Angiosperms
Clade:Monocots
Clade:Commelinids
Order:Zingiberales
Family:Zingiberaceae
Genus:Curcuma
Species:C. longa
Binomial name
Curcuma longa
L.[1]
Synonyms
Curcurma domestica Valeton
Turmeric (/ˈtɜːrmərɪk/)[2] is a rhizomatous herbaceous perennial plant (Curcuma longa) of the ginger family, Zingiberaceae.[3] It is native to Southeast Asia, and requires temperatures between 20 and 30 °C (68 and 86 °F) and a considerable amount of annual rainfall to thrive. Plants are gathered annually for their rhizomes and propagated from some of those rhizomes in the following season.
When not used fresh, the rhizomes are boiled for about 30–45 minutes and then dried in hot ovens, after which they are ground into a deep-orange-yellow powder[4] commonly used as a coloring and flavoring agent in the cuisines of BangladeshIndiaIndonesiaIran, and Pakistan, especially for curries, as well as for dyeing.
Although long-used in Ayurvedic medicine to treat various diseases, there is little high-quality clinical evidence for use of turmeric or its main constituent, curcumin, as a therapy.[5][6]
Botanical view of Curcuma longa

History[edit]

Turmeric has been used in Asia for thousands of years and is a major part of AyurvedaSiddha medicineUnani, and traditional Chinese medicine.[7] It was first used as a dye, and then later for its medicinal properties.[8]

Etymology[edit]

The origin of the name is uncertain. It possibly derives from Middle English or Early Modern English as turmeryte or tarmaret. It may be of Latin origin, terra merita ("meritorious earth").[9] The name of the genus, Curcuma, is derived from the Sanskrit kuṅkuma, referring to both turmeric and saffron, used in India since ancient times.[10]

Botanical description[edit]

Appearance[edit]

Turmeric is a perennial herbaceous plant that reaches up to 1 m (3 ft 3 in) tall. Highly branched, yellow to orange, cylindrical, aromatic rhizomes are found. The leaves are alternate and arranged in two rows. They are divided into leaf sheath, petiole, and leaf blade.[11] From the leaf sheaths, a false stem is formed. The petiole is 50 to 115 cm (20 to 45 in) long. The simple leaf blades are usually 76 to 115 cm (30 to 45 in) long and rarely up to 230 cm (91 in). They have a width of 38 to 45 cm (15 to 18 in) and are oblong to elliptic, narrowing at the tip.

Inflorescence, flower, and fruit[edit]

Turmeric flower
Wild turmeric, Australia
In China, the flowering time is usually in August. Terminally on the false stem is a 12 to 20 cm (4.7 to 7.9 in) long inflorescencestem containing many flowers. The bracts are light green and ovate to oblong with a blunt upper end with a length of 3 to 5 cm (1.2 to 2.0 in).
At the top of the inflorescence, stem bracts are present on which no flowers occur; these are white to green and sometimes, tinged reddish-purple, and the upper ends are tapered.[12]
The hermaphrodite flowers are zygomorphic and threefold. The three 0.8 to 1.2 cm (0.3 to 0.5 in) long sepals are fused, white, have fluffy hairs and the three calyx teeth are unequal. The three bright-yellow petals are fused into a corolla tube up to 3 cm (1.2 in) long. The three corolla lobes have a length of 1.0 to 1.5 cm (0.39 to 0.59 in) and are triangular with soft-spiny upper ends. While the average corolla lobe is larger than the two lateral, only the median stamen of the inner circle is fertile. The dust bag is spurred at its base. All other stamens are converted to staminodes. The outer staminodes are shorter than the labellum. The labellum is yellowish, with a yellow ribbon in its center and it is obovate, with a length from 1.2 to 2.0 cm (0.47 to 0.79 in). Three carpels are under a constant, trilobed ovary adherent, which is sparsely hairy. The fruit capsule opens with three compartments.[13][14][15]

Phytochemistry[edit]

Curcumin keto form
Curcumin enol form
Phytochemical components of turmeric include compounds called curcuminoids, such as curcumin (diferuloylmethane), demethoxycurcumin, and bisdemethoxycurcumin. Curcumin constitutes 3.14% (on average) of powdered turmeric, having variations in content among the species of Curcuma longa.[16] In addition, volatile oils include turmeroneatlantone, and zingiberene.[citation needed] Other constituents are sugarsproteins, and resins.[17]

Uses[edit]

Traditional medicine[edit]

Turmeric grows wild in the forests of South and Southeast Asia where it is collected for use in Indian traditional medicine (also called Siddha or Ayurveda).[5] From clinical research, there is no high-quality evidence that turmeric has medicinal properties.[5]

Culinary[edit]

Turmeric powder
Turmeric rhizome and powder
Curry using turmeric, referred to as haldi ki Sabji, a dish from India
Ganghwang-bap (turmeric rice)
Turmeric is one of the key ingredients in many Asian dishes. Its use as a coloring agent is not of primary value in South Asian cuisine.
Turmeric is used mostly in savory dishes, but also is used in some sweet dishes, such as the cake sfouf. In India, turmeric plant leaf is used to prepare special sweet dishes, patoleo, by layering rice flour and coconut-jaggery mixture on the leaf, then closing and steaming it in a special copper steamer (goa).
In recipes outside South Asia, turmeric sometimes is used as an agent to impart a golden yellow color. It is used in canned beverages, baked products, dairy products, ice cream, yogurt, yellow cakes, orange juice, biscuits, popcorn color, cereals, sauces, gelatins, etc. It is a significant ingredient in most commercial curry powders.
Most turmeric is used in the form of rhizome powder. In some regions (especially in MaharashtraGoaKonkan, and Kanara), turmeric leaves are used to wrap and cook food. Turmeric leaves are mainly used in this way in areas where turmeric is grown locally, since the leaves used are freshly picked. Turmeric leaves impart a distinctive flavor.
Although typically used in its dried, powdered form, turmeric also is used fresh, like ginger. It has numerous uses in East Asian recipes, such as pickle that contains large chunks of soft turmeric, made from fresh turmeric.
Turmeric is used widely as a spice in South Asian and Middle Eastern cooking. Many Persian dishes use turmeric as a starter ingredient. Various Iranian khoresh dishes are started using onions caramelized in oil and turmeric, followed by other ingredients. The Moroccan spice mix ras el hanout typically includes turmeric.
In India and Nepal, turmeric is widely grown and extensively used in many vegetable and meat dishes for its color. It also is used in Nepal for its supposed value in traditional medicine.
In South Africa, turmeric is used to give boiled white rice a golden colour.
In Vietnamese cuisine, turmeric powder is used to color and enhance the flavors of certain dishes, such as bánh xèo, bánh khọt, and mi quang. The powder is used in many other Vietnamese stir-fried and soup dishes.
The staple Cambodian curry paste kroeung, used in many dishes including Amok, typically contains fresh turmeric.
In Indonesia, turmeric leaves are used for Minang or Padang curry base of Sumatra, such as rendangsate padang, and many other varieties.
In Thailand, fresh turmeric rhizomes are used widely in many dishes, in particular in the southern Thai cuisine, such as the yellow curry and turmeric soup.
In medieval Europe, turmeric became known as Indian saffron because it was used widely as an alternative to the far more expensive saffron spice.

Dye[edit]

Turmeric makes a poor fabric dye, as it is not very light fast, but is commonly used in Indian and Bangladeshi clothing, such as saris and Buddhist monks's robes.[18] Turmeric (coded as E100, when used as a food additive),[19] is used to protect food products from sunlight. The oleoresin is used for oil-containing products. A curcumin and polysorbate solution or curcumin powder dissolved in alcohol is used for water-containing products. Over-coloring, such as in picklesrelishes, and mustard, is sometimes used to compensate for fading.
In combination with annatto (E160b), turmeric has been used to color cheesesyogurt, dry mixes, salad dressings, winter butter, and margarine. Turmeric also is used to give a yellow color to some prepared mustards, canned chicken broths, and other foods (often as a much cheaper replacement for saffron).[20]

Indicator[edit]

Turmeric paper, also called curcuma paper or in German literature, Curcumapapier, is paper steeped in a tincture of turmeric and allowed to dry. It is used in chemical analysis as an indicator for acidity and alkalinity.[21] The paper is yellow in acidic and neutral solutions and turns brown to reddish-brown in alkaline solutions, with transition between pH of 7.4 and 9.2.[22]

Traditional uses[edit]

Curcuma domestica Valeton, a drawing by A. Bernecker around 1860
In Ayurvedic and Siddha practices, turmeric has been used as an attempted treatment for a variety of internal disorders, such as indigestion, throat infections, common colds, or liver ailments, as well as topically, to cleanse wounds or treat skin sores.[5][6]
In Eastern India, the plant is used as one of the nine components of navapatrika along with young plantain or banana plant, taro leaves, barley (jayanti), wood apple (bilva), pomegranate (darimba), asokamanaka or manakochu, and rice paddy. The Navapatrika worship is an important part of Durga festival rituals.[23]
Haldi ceremony (called Gaye holud in Bengal) (literally "yellow on the body") is a ceremony observed during Hindu wedding celebrations in many parts of India including Bengal, Punjab, Maharashtra, and Gujarat.[24]
In Tamil Nadu and Andhra Pradesh, as a part of the Tamil/Telugu marriage ritual, dried turmeric tuber tied with string is used to create a Thali necklace, the equivalent of marriage rings in western cultures. In western and coastal India, during weddings of the Marathi and Konkani peopleKannada Brahmins turmeric tubers are tied with strings by the couple to their wrists during a ceremony, Kankanabandhana.[25]
Friedrich Ratzel reported in The History of Mankind during 1896, that in Micronesia, turmeric powder was applied for embellishment of body, clothing, utensils, and ceremonial uses.[26]

Adulteration[edit]

As turmeric and other spices are commonly sold by weight, the potential exists for powders of toxic, cheaper agents with a similar color to be added, such as lead(II,IV) oxide, giving turmeric an orange-red color instead of its native gold-yellow.[27]Another common adulterant in turmeric, metanil yellow (also known as acid yellow 36), is considered an illegal dye for use in foods by the British Food Standards Agency.[28]

Research[edit]

Claims that curcumin in turmeric may help to reduce inflammation have not been supported by strong studies.[5][6]
Turmeric or its principal constituent, curcumin, has been studied in numerous clinical trials for various human diseases and conditions, but the conclusions have either been uncertain or negative.[5][29][30]

Hedera (Falcarinol ) dược liệu kháng HL60

Hedera (Falcarinol ) dược liệu kháng HL60

From Wikipedia, the free encyclopedia
  (Redirected from Ivy)
Hedera
Hedera rhombea 4.JPG
Hedera rhombea, Aizu, Fukushima pref., Japan
Scientific classification
Kingdom:Plantae
(unranked):Angiosperms
(unranked):Eudicots
(unranked):Asterids
Order:Apiales
Family:Araliaceae
Subfamily:Aralioideae
Genus:Hedera
L.
Species
See text
Synonyms[1]
  • Helix Mitch.
  • Psedera Neck.
Hedera, commonly called ivy (plural ivies), is a genus of 12–15 species of evergreen climbing or ground-creeping woody plants in the family Araliaceae, native to western, central and southern EuropeMacaronesia, northwestern Africa and across central-southern Asia east to Japan and Taiwan.

Description[edit]

Hedera helix adult leaves and unripe berries in Ayrshire, Scotland
On level ground they remain creeping, not exceeding 5–20 cm height, but on suitable surfaces for climbing, including trees, natural rock outcrops or man-made structures such as quarry rock faces or built masonry and wooden structures, they can climb to at least 30 m above the ground. Ivies have two leaf types, with palmately lobed juvenile leaves on creeping and climbing stems and unlobed cordate adult leaves on fertile flowering stems exposed to full sun, usually high in the crowns of trees or the tops of rock faces, from 2 m or more above ground. The juvenile and adult shoots also differ, the former being slender, flexible and scrambling or climbing with small aerial roots to affix the shoot to the substrate (rock or tree bark), the latter thicker, self-supporting and without roots. The flowers are greenish-yellow with five small petals; they are produced in umbels in autumn to early winter and are very rich in nectar. The fruit is a greenish-black, dark purple or (rarely) yellow berry 5–10 mm diameter with one to five seeds, ripening in late winter to mid-spring. The seeds are dispersed by birds which eat the berries.
The species differ in detail of the leaf shape and size (particularly of the juvenile leaves) and in the structure of the leaf trichomes, and also in the size and, to a lesser extent, the colour of the flowers and fruit. The chromosome number also differs between species. The basic diploid number is 48, while some are tetraploid with 96, and others hexaploid with 144 and octaploid with 192 chromosomes.[2]

Ecology[edit]

Ivies are natives of Eurasia and North Africa but have been introduced to North America and Australia. They invade disturbed forest areas in North America and in Europe.[3] Ivy seeds are spread by birds.[3]
Ivies are of major ecological importance for their nectar and fruit production, both produced at times of the year when few other nectar or fruit sources are available.[4] The ivy bee Colletes hederae is completely dependent on ivy flowers, timing its entire life cycle around ivy flowering.[5] The fruit are eaten by a range of birds, including thrushesblackcaps, and woodpigeons.[4] The leaves are eaten by the larvae of some species of Lepidoptera such as angle shadeslesser broad-bordered yellow underwingscalloped hazelsmall angle shadessmall dusty wave (which feeds exclusively on ivy), swallow-tailed moth and willow beauty.

Taxonomy[edit]

The following species are widely accepted; they are divided into two main groups, depending on whether they have scale-like or stellate trichomes on the undersides of the leaves:[2][6][7]
  • Trichomes scale-like
  • Trichomes stellate
    • Hedera azorica Carrière – Azores ivy. Azores.
    • Hedera helix L. – Common ivy (syn. H. caucasigena Pojark., H. taurica (Hibberd) Carrière). Europe, widespread.
    • Hedera hibernica (G.Kirchn.) Bean – Atlantic ivy (syn. H. helix subsp. hibernica (G.Kirchn.) D.C.McClint.). Atlantic western Europe.
The species of ivy are largely allopatric and closely related, and many have on occasion been treated as varieties or subspecies of H. helix, the first species described. Several additional species have been described in the southern parts of the former Soviet Union, but are not regarded as distinct by most botanists.
The only verified hybrid involving ivies is the intergeneric hybrid × Fatshedera lizei, a cross between Fatsia japonica and Hedera hibernica. This hybrid was produced once in a garden in France in 1910 and never successfully repeated, the hybrid being maintained in cultivation by vegetative propagation.[8][9] Despite the close relationship between Hedera helix and H. hibernica (until relatively recently considered conspecific), no hybrids between them have yet been found.[10] Hybridisation may however have played a part in the evolution of some species in the genus.[2]

Uses and cultivation[edit]

When the ivy blooms in September it attracts hoverfliesand other nectar feeders.
A variegated Hedera helixcultivar
Ivies are very popular in cultivation within their native range and compatible climates elsewhere, for their evergreen foliage, attracting wildlife, and for adaptable design uses in narrow planting spaces and on tall or wide walls for aesthetic addition, or to hide unsightly walls, fences and tree stumps. Numerous cultivars with variegated foliage and/or unusual leaf shapes have been selected for horticultural use.[8]

Problems and dangers[edit]

On trees[edit]

Much discussion has involved whether or not ivy climbing trees will harm them. In Europe, the harm is generally minor although there can be competition for soil nutrients, light, and water, and senescent trees supporting heavy ivy growth can be liable to windthrowdamage.[4] Harm and problems are more significant in North America, where ivy is without the natural pests and diseases that control its vigour in its native continents; the photosynthesis or structural strength of a tree can be overwhelmed by aggressive ivy growth leading to death directly or by opportunistic disease and insect attacks caused by weakness from the duress.[citation needed]

Invasive exotic[edit]

Several ivy species have become a serious invasive species (invasive exotic) in natural native plant habitats, especially riparian and woodland types, and also a horticultural weed in gardens of the western and southern regions of North America with milder winters. Ivies create a dense, vigorously smothering, shade-tolerant evergreen groundcover that can spread through assertive underground rhizomes and above-ground runners quickly over large natural plant community areas and outcompete the native vegetation. The use of ivies as ornamental plants in horticulture in California and other states is now discouraged or banned in certain jurisdictions.[11] Similar problems exist in Australia. For example, in both countries the North African drought-tolerant H. canariensis and H. algeriensis and European H. helix were originally cultivated in garden, park, and highway landscaping, but they have become aggressively invasive in coastal forests and riparian ecosystems, now necessitating costly eradication programs.[12]

Toxicity[edit]

The berries are moderately toxic. Ivy foliage contains triterpenoid saponins and falcarinol. Falcarinol is capable of inducing contact dermatitis. It has also been shown to kill breast cancer cells.[13]

Etymology and other names[edit]

The name ivy derives from Old English ifig, cognate with German Efeu, of unknown original meaning.[14] The scientific name Hedera is the classical Latin name for the plant.[8] Old regional common names in Britain, no longer used, include "Bindwood" and "Lovestone", for the way it clings and grows over stones and bricks. US Pacific Coast regional common names for H. canariensis include "California ivy" and "Algerian ivy"; for H. helix, regional common names include the generic "English ivy".
The name ivy has also been used as a common name for a number of other unrelated plants, including Boston ivy (Japanese Creeper Parthenocissus tricuspidata, in the family Vitaceae), Cape-ivy or German-ivy (Delairea odorata in the family Asteraceae), poison-ivy (Toxicodendron radicans in the family Anacardiaceae), and Swedish ivy (Whorled Plectranthus Plectranthus verticillatus, in the family Lamiaceae).

Gallery[edit]