Tuesday, 4 July 2017

Galangin kháng bel-7402

Study on apoptosis of BEL-7402 cells induced by galangin

Galangin kháng bel-7402

From Wikipedia, the free encyclopedia
Galangin
Skeletal formula of galangin
Ball-and-stick model of the galangin molecule
Names
IUPAC name
3,5,7-Trihydroxy-2-phenylchromen-4-one
Other names
Norizalpinin
3,5,7-Trihydroxyflavone
3,5,7-triOH-Flavone
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard100.008.147
KEGG
PubChem CID
UNII
Properties
C15H10O5
Molar mass270.24 g·mol−1
Density1.579 g/mL
Melting point214 to 215 °C (417 to 419 °F; 487 to 488 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Galangin is a flavonol, a type of flavonoid.

Occurrence[edit]

Galangin is found in high concentrations in Alpinia officinarum (lesser galangal)[1] and Helichrysum aureonitens.[2] It is also found in the rhizome of Alpinia galanga[3] and in propolis.[4]

Biological activities[edit]

Galangin has been shown to have in vitro antibacterial[5][6] and antiviral activity.[7] It also inhibits the growth of breast tumor cells in vitro.[8][9]

Photinia serratifolia kháng Bel-7402

Chemical composition, cytotoxic and antioxidant activity of the leaf essential oil of Photinia serrulata

Photinia serratifolia kháng Bel-7402

From Wikipedia, the free encyclopedia
  (Redirected from Photinia serrulata)
Photinia serratifolia
Photinia serratifolia CReal.jpg
Scientific classification
Kingdom:Plantae
(unranked):Angiosperms
(unranked):Eudicots
(unranked):Rosids
Order:Rosales
Family:Rosaceae
Genus:Photinia
Species:P. serratifolia
Binomial name
Photinia serratifolia
(Desf.Kalkman
Synonyms[1]
Photinia serratifolia (syn. Photinia serrulata), commonly called Taiwanese photinia[2] or Chinese photinia is a flowering shrub or tree in the Rosaceae family of flowering plants, found in mixed forests of China, Taiwan, Japan, the Philippines, Indonesia, and India. It grows typically 4–6 m (13–20 ft), sometimes up to 12 m (39 ft), tall.[3] Its leaves are toxic due to the presence of cyanogenic glycosides.[4]

References[edit]

  1. Jump up^ Germplasm Resources Information Network (GRIN)
  2. Jump up^ "Photinia serratifolia"Natural Resources Conservation Service PLANTS Database. USDA. Retrieved 30 September 2015.
  3. Jump up^ Lu, Lingdi; Spongberg, Stephen A., Flora of China entry for Photinia serratifolia (Vol. 9 Page 125), Missouri Botanical Garden & Harvard University Herbaria, retrieved 2009 Check date values in: |access-date= (help)
  4. Jump up^ K. A. Jacobs, F. S. Santamour, Jr., G. R. Johnson, M. A. Dirrs (September 1996). "Differential Resistance to Entomosporium Leafspot Disease and Hydrogen Cyanide Potential in Photinia"(PDF)J. Environ. Hort14 (3): 154–157.

Pinene kháng Bel-7402

[HTML] Anti-tumor effect of α-pinene on human hepatoma cell lines through inducing G2/M cell cycle arrest

Pinene kháng Bel-7402

From Wikipedia, the free encyclopedia
Pinene
Pinene
Names
IUPAC names
(1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
(1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane
Identifiers
ECHA InfoCard100.029.170
Properties
C10H16
Molar mass136.24 g/mol
AppearanceLiquid
Density0,86 g·cm−3 (alpha, 15 °C)[1][2]
Melting point−62 to −55 °C (−80 to −67 °F; 211 to 218 K) (alpha)[1]
Boiling point155 to 156 °C (311 to 313 °F; 428 to 429 K) (alpha)[1]
Practically insoluble in water
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 verify (what is Yes ?)
Infobox references
Pinene (C10H16) is a bicyclic monoterpene chemical compound.[1] There are two structural isomers of pinene found in nature: α-pinene and β-pinene. As the name suggests, both forms are important constituents of pine resin; they are also found in the resins of many other conifers, as well as in non-coniferous plants such as camphorweed (Heterotheca)[3] and big sagebrush (Artemisia tridentata). Both isomers are used by many insects in their chemical communication system. The two isomers of pinene constitute the major component of turpentine.

Isomers[edit]

skeletal formula
(1R)-(+)-alpha-pinene-2D-skeletal.png
(1S)-(-)-alpha-pinene-2D-skeletal.png
(1R)-(+)-beta-pinene-2D-skeletal.png
(1S)-(-)-beta-pinene-2D-skeletal.png
perspective view
X
(1S)-(-)-alpha-pinene-2D-projected-skeletal.png
X
(1S)-(-)-beta-pinene-2D-projected-skeletal.png
ball-and-stick model
X
(1S)-(−)-alpha-pinene-from-xtal-3D-balls.png
X
(1S)-(−)-beta-pinene-from-xtal-3D-balls.png
name
(1R)-(+)-α-pinene
(1S)-(−)-α-pinene
(1R)-(+)-β-pinene
(1S)-(−)-β-pinene
CAS number
7785-70-8
7785-26-4
19902-08-0
18172-67-3

Biosynthesis[edit]

α-Pinene and β-pinene are both produced from geranyl pyrophosphate, via cyclisation of linaloyl pyrophosphate followed by loss of a proton from the carbocation equivalent.
Biosynthesis of pinene from geranyl pyrophosphate

Plants[edit]

Alpha-pinene is the most widely encountered terpenoid in nature[4] and is highly repellant to insects.[5]
Alpha-pinene appears in conifers and numerous other plants.[6] Pinene is a major component of the essential oils of Sideritis spp. (ironwort)[7] and Salvia spp. (sage).[8]Cannabis also contains alpha-pinene.[6] Resin from Pistacia terebinthus (commonly known as terebinth or turpentine tree) is rich in pinene. Pine nuts produced by pinetrees contain pinene.[6]
Makrut lime fruit peel contains an essential oil comparable to lime fruit peel oil; its main components are limonene and β-pinene.[9]

Usage[edit]

In chemical industry, selective oxidation of pinene with some catalysts gives many compounds for perfumery, such as artificial odorants. An important oxidation product is verbenone, along with pinene oxide, verbenol and verbenyl hydroperoxide. [10]
Pinene left verbenone right
Pinenes are the primary constituents of turpentine.
Pinene has also been used as anti-cancer agent in Traditional Chinese medicine, also for its anti-inflammatory, antiseptic, expectorant and bronchodilator properties.[11]