Sunday, 11 June 2017

Tetramethylpyrazine hợp chất kháng HL60

Tetramethylpyrazine potentiates arsenic trioxide activity against HL ...

Tetramethylpyrazine

From Wikipedia, the free encyclopedia
Tetramethylpyrazine
Tetramethylpyrazine.svg
Names
IUPAC name
Other names
Ligustrazine; Tetrapyrazine
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard100.013.084
EC Number214-391-2
PubChem CID
UNII
Properties
C8H12N2
Molar mass136.20 g·mol−1
Melting point84–86 °C (183–187 °F; 357–359 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tetramethylpyrazine, also known as ligustrazine, is an antiinflammatory compound isolated from the fermented food natto. When purified, it is a colorless solid. Its biosynthesis involves amination of acetoin, the latter derived from pyruvate.[1]
The compound has attracted much attention for its medicinal properties.[2][2] and in fermented cocoa beans.[3]
It exhibited in vivo nootropic activity in rats.[4]

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