Phân tích protein của phản ứng phân tử của các tế bào Raji để maslinic ..
Maslinic acid kháng Raji
From Wikipedia, the free encyclopedia
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| Names | |
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| IUPAC name
(4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
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| Systematic IUPAC name
(2α,3β)-2,3-Dihydroxyolean-12-en-28-oic acid
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| Other names
Crategolic acid; Masilinic acid; Crataegolic acid
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.128.873 |
| KEGG | |
PubChem CID
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| Properties | |
| C30H48O4 | |
| Molar mass | 472.71 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is   ?) | |
| Infobox references | |
Maslinic acid is a compound derived from dry olive-pomace oil (an olive skin wax) which is a byproduct of olive oil extraction. It is a member of the group of triterpenes known as oleananes.
Pharmacology[edit]
In vitro study shows that maslinic acid inhibits serine proteases, key enzymes necessary for the spread of HIV within an individual's body.[1] It also has in vitro antiproliferative effects on colon cancer cells.[2] Maslinic acid increases EAAT2 (GLT-1) glutamate reuptake and may reduce glutamatergic toxicity in rats.[3]
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